Continued from page 1

Current vitamin D supplements available in the U.S. are not ideal. Solitary vitamin D preparations (containing up to 8000 IU/mL) are too concentrated to be safe for routine home use, therefore are reserved only for clinical use. Other vitamin D supplements are available as multivitamin preparations, which contain 400 IU of vitamin D per mL, but may also provide unnecessary supplementation of other nutrients including vitamin A, C, E and K or iron, zinc and B vitamins. It should be noted that although there are generic forms of the multivitamin preparations, the commercial brands Tri-Vi-Sol and Poly-Vi-Sol are produced by the two major formula manufacturers in the U.S., who routinely violate the International Code of Marketing of Breastmilk Substitutes.

In conclusion, breastfeeding remains the foundation of normal health and development; the original paradigm for nourishing and nurturing young human beings. The AAP policy recommending vitamin D supplementation in breastfed infants may appear to suggest that breastmilk is somehow inadequate. However, it is the social and environmental challenges of sunlight deficiency that may contribute to the issue of vitamin D deficiency and rickets. The decision to supplement vitamin D ultimately lies with parents or caregivers once they are presented with the facts. It is the role of the health care professionals to promote and protect breastfeeding while informing families on the risk of vitamin D deficiency.

In practice, the health care professional should continue to be attentive to those breastfed infants at highest risk when recommending supplementation. This includes those individuals with darker skin pigmentation and limited sunlight exposure. Future research is needed to examine the effects of vitamin D supplementation on exclusively breastfed babies, as well as the impact of supplementation on the initiation and duration of breastfeeding.

References:

  1. Gartner, L.M., Greer, F.R. and Section on Breastfeeding and Committee on Nutrition. Prevention of Rickets and Vitamin D Deficiency: New Guidelines for Vitamin D Intake. Pediatrics Vol. 111 No. 4 April 2003, pp. 908-910.
  2. AAP Work Group on Breastfeeding. Breastfeeding and the Use of Human Milk. Pediatrics Vol 100 No.6 December 1997, pp 1035-1039.
  3. Institute of Medicine, Food and Nutrition Board, Standing Committee on the Scientific Evaluation of Dietary Reference Intakes. Vitamin D. In: Dietary Reference Intakes for Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride. Washington, DC: National Academy Press; 1997:250-287.
  4. Reeve, L.E., Chesney, R.W., DeLuca, H.F. Vitamin D of human milk: identification of biologically active forms. Am J Clin Nutr.1982; 36 :122 -126.
  5. Hollis, B.W., Roos, B.A., Draper, H.H., Lambert, P.W. Vitamin D and its metabolites in human and bovine milk. J Nutr.1981; 111 :1240 -1248.
  6. Lammi-Keefe, C.J. Vitamins D and E in human milk. In: Jensen RG, ed. Handbook of Milk Composition. San Diego, CA: Academic Press; 1995:706-717.
  7. Kreiter, S.R., Schwartz, R.P., Kirkman, H.N. Jr., Charlton, P.A., Calikoglu, A.S., Davenport, M.L. Nutritional rickets in African American breast-fed infants. J Pediatr. 2000; 137 :153 -157.
  8. Vitamin D Expert Panel Meeting (2001, October 11-12). CDC, Atlanta, Georgia. Retrieved April 20, 2003 from the World Wide Web: http://www.cdc.gov/nccdphp/dnpa/nutrition/
    pdf/Vitamin_D_Expert_Panel_Meeting.pdf
Research Corner
Continued from page 8
  1. The three subscores of the MAACL-R (anxiety, depression, hostility) were not correlated with salivary cortisol or α-amylase, or with milk volume.
  2. Both salivary α-amylase and cortisol levels decreased with experience with the pumping procedure.
  3. Salivary α-amylase concentrations were highly negatively correlated with plasma PRL, but not with oxytocin. Salivary α-amylase correlates with plasma norepinephrine as a measure of stress.

Usually, a stress response, including psychological stress, is associated with an increase in PRL. However this process may be reversed under conditions in which PRL levels are normally elevated, such as pregnancy and lactation. As

plasma PRL was decreased when salivary a-amylase was elevated, the investigators hypothesized that the stress associated with preterm deliveries may result in inadequate lactation through an adrenergic mechanism.

Take home message: We don't understand all the hormonal components of milk production or stress, but more pumping is better, and double pumping may be better than single. Mothers of preterm infants should be expected to produce the same amount of milk as mothers of term infants.

References:

  1. Chatterton, R.T., Hill, P.D., Aldag, J.C. et al. Relation of plasma oxytocin and prolactin concentrations to milk production in mothers of preterm infants: influence of stress. J Clin Endocrinol Metab 2000;85:3661-8.

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