Family Breastfeeding Information Sheet
Occasionally mothers may have difficulty establishing or maintaining breastmilk production, such as:
- Extended breastpumping for a premature or ill newborn
- An ill mother
- Need for temporary weaning, then restarting breastfeeding
- Nursing an adopted infant
- Nursing after breast surgery
Reglan®(Metoclopramide) is a drug used in infants, children and adults to improve upper gastrointestinal function.
- In infants, it is often used to treat gastroesophageal reflux (vomiting).
- In children and adults, it is used to treat heartburn, and to treat the nausea and
vomiting caused by other drugs.
Reglan®(Metoclopramide) has, as a side effect, the ability to increase prolactin, the milk- making hormone in the brain.
- Prolactin, along with frequent and regular breast pumping, increases breastmilk production.
Reglan®(Metoclopramide) is usually taken as a 10 mg tablet orally, three or four times a day for a week, then tapered off over the next week.
- Cost for 30 tablets is approximately $33 for the brand name Reglan® and $12-15 for the generic brand which is just as effective.
- Milk supply usually increases within 2-4 days of starting the medication and pumping 6-8 times per 24 hours.
- It is essential that the milk be emptied frequently from your breasts, even at
night.
Although Reglan®(Metoclopramide) can be safely given to infants, a small amount of mother's dose will get into the milk.
- Studies have shown no infant side effects, but
- Watch for sleepiness and poor feeding in your infant.
Side effects may occur in a small number of mothers.
Restlessness, drowsiness, fatigue and diarrhea may occur, but usually do not require
stopping the medication. Driving while taking the medication may not be wise if you are
feeling fatigued.
- Rare side effects are: sleeplessness, headache, confusion, dizziness, mental depression, feelings of anxiety and aggitation. If you have any of these, discontinue the drug.
- A very rare side effect (less than 1 per 500 people taking the drug) is an "acute dystonic reaction" where you have difficulty controlling your muscles movements, including your eye movements. Discontinue the drug and call your physician. Benedryl (diphenhydramine) will stop this reaction.
Reglan®(Metoclopramide) should NOT be used if you:
- Have epilepsy or are on anti-seizure medications
- Have a history of mental depression or are on antidepressant drugs
- Have a tumor called a Pheochromocytoma or uncontrolled high blood pressure
- Have intestinal bleeding or obstruction
- Have a known allergy or prior reaction to Reglan®(Metoclopramide)
For further information, or if you have any concerns, consult your, or your baby's
physician.
References
Budd SS, Erdman SH, Long DM et al: Improved Lactation with metoclopramide. A case report. Clin Pediatr 32: 53, 1993
Ehrenkrantz RA, Ackerman BA: Metoclopramide effect on faltering milk production by mothers of premature infants, Pediatrics 78: 614, 1986
Gupta AP & Gupta PK: Metoclopramide as a lactogogue. Clin Pediatr 24(5): 269-272, 1985
Lawrence RA: Breastfeeding: A Guide for the medical profession, 4th Ed. Mosby, St Louis, MO, 1994
Physicians' Desk Reference, 49th Ed, Medical Economics, Montvale, NJ, 1995
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